Previously Offered (depleted) Tissue Microarrays

  1. CHTN2002T1 - "Test" TMA

    Description:

    TMA series CHTN2002T1 contains 5 human tissue types (colonic mucosa, endometrium, spleen, liver and uterine smooth muscle) in 0.6 mm and 2 mm spot sizes. These are useful for determining assay conditions and procedures before using more expensive comprehensiveTMA slides.

    Unstained histologic sections are 4 microns thick, on charged glass slides.

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  2. CHTN2003CRCprog - Colorectal Carcinoma Progression

    Description:

    The CHTN2003CRCprog TMA contains up to 20 cases of non-neoplastic colonic mucosa, 14 cases of adenomatous polyps, 14 cases of primary colorectal adenocarcinomas, 7 cases of adenocarcinoma metastatic to regional lymph nodes and 7 cases of adenocarcinoma metastatic to distant sites. Each case is sampled three times with 0.6 mm cores.

    This TMA represents a limited number of cases that may detect strong trends in differential gene expression, and is intended for pilot surveys and generation of hypotheses. This TMA does not contain case numbers of sufficient quantity to prove the clinical utility of a marker.

    Unstained histologic sections are 4 microns thick, on charged glass slides.

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  3. CHTN BrCaProg1 - Brea​st Cancer Progression

    Description:

    The CHTNBrCaProg1 TMA contains non-neoplastic breast tissue, ductal carcinoma in situ (DCIS), infiltrating ductal carcinoma of the breast, infiltrating lobular carcinoma of the breast, and cases of adenocarcinoma metastatic to regional lymph nodes. Each case is sampled one time with a 2 mm core. The TMA design includes 14 cases of non-neoplastic breast, 14 cases of DCIS, 21 cases of primary carcinoma and 7 cases of metastatic carcinoma. Histologic quality assurance limits ensure a minimum of 7 cases of non-neoplastic breast, 10 cases of infiltrating carcinoma primary to the breast and 4 cases of metatstatic carcinoma. Due to the difficulty in capturing pre-invasive neoplasia, a minimum number of DCIS cases is not being guaranteed.

    This TMA represents a limited number of cases that may detect strong trends in differential gene expression, and is intended for pilot surveys and generation of hypotheses. This TMA does not contain case numbers of sufficient quantity to prove the clinical utility of a marker.

    Unstained histologic sections are 4 microns thick, on charged glass slides.

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  4. CHTN OvCa1 - Ovarian Carcinoma Survey

    Description:

    The CHTN OvCa1 TMA contains examples of the major histologic types of epithelial ovarian cancer . Each case is sampled four times with 0.6 mm cores. The TMA design includes 20 cases each of serous papillary carcinoma (well to moderately differentiated), clear cell carcinoma, endometrioid adenocarcinoma and mucinous adenocarcinoma). Another 20 cases of poorly and undifferentiated carcinoma are also provided.

    This TMA may detect strong trends in differential gene expression among the different histologic types of ovarian carcinoma, and is intended for pilot surveys and generation of hypotheses. This TMA is not designed to prove the clinical utility of prognostic biomarkers.

    Unstained histologic sections are 4 microns thick on charged glass slides.

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